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Biologic therapy

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Targeted Treatments for Allergies and Asthma

For patients whose symptoms aren’t fully controlled with standard medications, biologic therapies can be a game-changer. These advanced treatments work at the immune system level to reduce inflammation, prevent flare-ups, and improve quality of life.

Biologics we offer:

  • Xolair® (omalizumab)
  • Nucala® (mepolizumab)
  • Fasenra® (benralizumab)
  • Dupixent® (dupilumab)
  • Adbry™ (tralokinumab-ldrm)
  • Tezspire® (tezepelumab-ekko)

How Biologics Work

Biologics are made from naturally occurring proteins or antibodies that are designed to target specific molecules in your immune system. By blocking the pathways that trigger allergic inflammation, they help reduce symptoms, lower the frequency of flare-ups, and may allow you to use fewer oral steroids. These medications are given by injection, usually every 2–8 weeks, and are tailored to your diagnosis, age, and allergy profile.

Available Biologic Therapies

Xolair® (omalizumab)

  • Targets: IgE (immunoglobulin E)
  • Approved Uses:
    Food allergy
    • Moderate to severe allergic asthma (ages 6+)
    • Chronic idiopathic urticaria (hives) (ages 12+)
    • Nasal polyps (adults)
  • Benefit: Reduces allergic inflammation and frequency of asthma attack, sinonasal symptoms, hives +/- angioedema, and accidental food allergy reactions

Nucala® (mepolizumab)

  • Targets: Interleukin-5 (IL-5) to reduce eosinophils
  • Approved Uses:
    • Severe eosinophilic asthma (ages 6+)
    • Hypereosinophilic Syndrome (HES) (ages 12+)
    • Eosinophilic Granulomatosis with Polyangiitis (EGPA) (adults)
    • Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) (adults)
  • Benefit: Controls asthma and eosinophil-related conditions by lowering eosinophil levels.

Fasenra® (benralizumab)

  • Targets: IL-5 receptor to directly destroy eosinophils
  • Approved Uses:
    • Severe eosinophilic asthma (ages 12+)
  • Benefit: Reduces asthma flare-ups and may decrease the need for oral steroids.

Dupixent® (dupilumab)

  • Targets: IL-4 and IL-13 pathways involved in allergic inflammation
  • Approved Uses:
    • Moderate to severe atopic dermatitis (ages 6+)
    • Moderate to severe asthma with elevated eosinophils (ages 6+)
    • CRSwNP (adults)
    • Eosinophilic esophagitis (EoE) (ages 1+, ≥15 kg)
    • Prurigo nodularis (adults)
    • CSU
  • Benefit: Improves skin, breathing, and sinus symptoms while reducing inflammation.

Adbry™ (tralokinumab-ldrm)

  • Targets: IL-13, a key driver of inflammation in eczema
  • Approved Uses:
    • Moderate to severe atopic dermatitis (adults)
  • Benefit: Reduces eczema flare-ups, itching, and skin inflammation.

Tezspire® (tezepelumab-ekko)

  • Targets: Thymic stromal lymphopoietin (TSLP), an early trigger of airway inflammation
  • Approved Uses:
    • Severe asthma (ages 12+), regardless of eosinophil level
  • Benefit: Offers broad asthma control, even for patients without high eosinophil counts.

Is a Biologic Right for You?

Biologic treatments may be an option if you:

  • Have moderate to severe asthma or allergic conditions not controlled by standard medications
  • Experience frequent flare-ups or ER visits
  • Have elevated inflammatory markers such as eosinophils or IgE
  • Meet specific FDA criteria for age and diagnosis
  • Suffer from chronic hives that are resistant to medical management
  • I think we have to add more content here for the other indications-  sinusitis etc

We’ll review your medical history, testing, and treatment response to determine the right biologic for you.

Take the Next Step in Your Treatment

If allergies, asthma, or inflammatory conditions are limiting your life, advanced biologic therapy could help. Contact us today to schedule a consultation and see if one of these treatments is right for you.